I know a guy with CHS that has never touched a concentrate or edible….just smoked lotsa joints and he has it. It’s hard to say what causes it, but it’s not solely a concentrate thing.
All that being said…..even when my tolerance is way up, and I’m not getting as high from a strain….. I still get the medicinal effects…pain relief etc. I wonder if CHS is the opposite side of the bell curve from the point where someone in tons of pain won’t get the psychoactive effects from weed….but still gets the medical side of things. It’s like the medicine goes where it’s needed if you really need it… I’m wondering if you’re taking a medicinal dose when you don’t need it, that’s what sets it off.