I grow at least 4 different strains every grow, and make edibles for sleep for me, and for daytime use for friends.
For me, rotating among about half a dozen different strains helps keep tolerance in check.
Last grow I did 4 different strains only (Barney's CriticalKush, Mephisto DoubleGrape, Zambeza SuperSilverHaze, Mephisto FantasmoExpress) and only one of them was barely acceptable for sleep, mephisto DoubleGrape.
I had thought the CriticalKush would be sleepy, but it was weak.
Even 4 strains wasn't enough.
I can't handle single strain grows, because that single strain might not work as well for me as something yet untried.