Live Stoner Chat Live Stoner Chat - Apr-Jun '22

[Dabber]

 

[Dabber]

 

[Mossy]

Starting it off right with a good joint and AFN LS

Start the day the Right way @Dabber ...nothing better....

 

[Dabber]

 

[Dabber]

@Need4Weed yo bro

 

[Dr Fluff]

I've just given you plus rep...and have to pass more around...... ..it is stunning.

When I were a young lass...the old guy two doors down had a beautiful Rhoddy tree....5ft trunk and a Crown of flower on the top....it was magnificent.

Every time I went topless sunbathing in my garden....he used to be up that tree on the ladders pruning...snip..snip..snip.........

When I Complpained to me mother she said....ay..why stop an old mans joy.............it is a beautiful tree...........

You know it was National bee day a couple of days ago, here is something i didn't get around to posting.
Mad honey
If bees forage on rhododendron the grayanotoxin-containing nectar would get processed in the hive to create toxin-laced honey 8. Since grayanotoxins are known to be toxic for humans this honey would be expected to exert some adverse, or at least interesting, effects.

And that’s exactly what is seen.

The most common cause of grayanotoxin poisoning in humans is from eating honey made by bees foraging on rhododendron. Small doses cause light-headedness and hallucinations. In large doses it is overtly toxic and induces the range of symptoms described above.

In Nepal and parts of Turkey this so-called ‘mad honey’ is deliberately produced. You can buy mad honey online … a snip at $199 for 250g 9.

As well as causing light headedness and hallucinations, mad honey is consumed – particularly in Turkey – because of its perceived therapeutic benefits for conditions such as diabetes, bowel disorders and hypertension. Perceived because I’m not sure there’s real evidence of benefits for any of these conditions.

Mad honey, or deli bal in Turkish, is also thought to enhance sexual performance 10. Perhaps unsurprisingly, mad honey poisoning is most commonly observed in middle-aged men

Rhododendron, bees and toxins
Rhododendron are insect pollinated and produce large amounts of sugar-rich nectar to ‘reward’ visiting pollinators. A number of species of bees are known to pollinate rhododendron, including honey bees. Surprisingly – for an insect pollinated plant – rhododendron nectar contains high levels of diterpines which are toxic to many different animals. These types of toxins are usually produced by plants to reduce foliar grazing.

The most important (by amount) diterpine in rhododendron nectar is grayanotoxin.

Grayanotoxin is a neurotoxin. It works, i.e. its toxicity is due to, interference with voltage-gated sodium channels (VGSC) in neurones. We’ve discussed VGSC’s before in the context of resistance of Varroa to Apistan.

Although the modes of action of apistan and grayanotoxin are different, the consequences are not. If you block neuronal activity, stuff 3 that’s important often stops working properly – ‘stuff’ like the heart

Symptoms of grayanotoxin poisoning include cardiovascular problems, nausea, vomiting and loss of consciousness.

But wait, there’s more. Add to that heady mix one or more of the following … blurred vision, dizziness, hypersalivation, perspiration, weakness and paresthesia4 in the extremities and around the mouth.

In higher doses, symptoms can include loss of coordination and severe, progressive, muscular weakness. Fatalities are rare but not unknown.

These are all symptoms in humans experiencing grayanotoxin poisoning.

Great … could it possibly get worse?

 

[Mossy]

Guess where I'm headed.............







Before it gets too Hot.....today is supposed to be the hottest day.....but a stiff breeze makes it a Lot more bearable than yesterday.....

 

[Dabber]

 

[Dabber]

@arty zan

 

[Mossy]

You know it was National bee day a couple of days ago, here is something i didn't get around to posting.
Mad honey
If bees forage on rhododendron the grayanotoxin-containing nectar would get processed in the hive to create toxin-laced honey 8. Since grayanotoxins are known to be toxic for humans this honey would be expected to exert some adverse, or at least interesting, effects.

And that’s exactly what is seen.

The most common cause of grayanotoxin poisoning in humans is from eating honey made by bees foraging on rhododendron. Small doses cause light-headedness and hallucinations. In large doses it is overtly toxic and induces the range of symptoms described above.

In Nepal and parts of Turkey this so-called ‘mad honey’ is deliberately produced. You can buy mad honey online … a snip at $199 for 250g 9.

As well as causing light headedness and hallucinations, mad honey is consumed – particularly in Turkey – because of its perceived therapeutic benefits for conditions such as diabetes, bowel disorders and hypertension. Perceived because I’m not sure there’s real evidence of benefits for any of these conditions.

Mad honey, or deli bal in Turkish, is also thought to enhance sexual performance 10. Perhaps unsurprisingly, mad honey poisoning is most commonly observed in middle-aged men

Rhododendron, bees and toxins
Rhododendron are insect pollinated and produce large amounts of sugar-rich nectar to ‘reward’ visiting pollinators. A number of species of bees are known to pollinate rhododendron, including honey bees. Surprisingly – for an insect pollinated plant – rhododendron nectar contains high levels of diterpines which are toxic to many different animals. These types of toxins are usually produced by plants to reduce foliar grazing.

The most important (by amount) diterpine in rhododendron nectar is grayanotoxin.

Grayanotoxin is a neurotoxin. It works, i.e. its toxicity is due to, interference with voltage-gated sodium channels (VGSC) in neurones. We’ve discussed VGSC’s before in the context of resistance of Varroa to Apistan.

Although the modes of action of apistan and grayanotoxin are different, the consequences are not. If you block neuronal activity, stuff 3 that’s important often stops working properly – ‘stuff’ like the heart

Symptoms of grayanotoxin poisoning include cardiovascular problems, nausea, vomiting and loss of consciousness.

But wait, there’s more. Add to that heady mix one or more of the following … blurred vision, dizziness, hypersalivation, perspiration, weakness and paresthesia4 in the extremities and around the mouth.

In higher doses, symptoms can include loss of coordination and severe, progressive, muscular weakness. Fatalities are rare but not unknown.

These are all symptoms in humans experiencing grayanotoxin poisoning.

Great … could it possibly get worse?

Morning @arty zan .....your brain is amazing...........I Wish I had it.....

I Hit a similar problem with Borage and Bees...too much and it gets Toxic...........