A whole room... Now that could be fun.
0ne suggestion I can make is to set things up physically so that you have good access to plants without moving them much. With that kind of space, you should be able to make maintenance of plants really easy.
If budget is a significant issue and you are up to a bit of wiring, have a look at the LEDs I put together in my signature grow. Even with my screwups, and with two smaller plants in my 24C's I came somewhere in the neighbourhood of 1g/watt used. I would have done better than that if I hadn't been pushing the light and nutes too hard. If you do set up screw ins, you could do panels of 6 bulbs each, and use 1 panel per large plant. Maybe 4 bulbs per plant would also work given the results some growers here are getting with single COBS. Using 15 bulbs per panel as I did was excessive, other than allowing adjustment of K by unscrewing bulbs without actually changing them.
Anyway, it looks as though you are in for some entertaining gardening time. Happy Growing!