I'm leaving the big fans that come out right with the nodes I'm leaving as my new mains, but everything else gets trimmed off. I did it once before with a grilled cheese plant and it didn't necessarily give a bigger yield, but the buds were more consistent from cola to cola and were nicely dense and sticky. I think flowering under better lights and if I can get the nutes a little better I'm hoping to plump up the buds more this time around. Different strains, though, so may get different results all around. Heck, the two Ghost Of LeeRoy's aren't fem seeds, so might even get a male or two. But for me, the mainlining is also just one other thing to try and play with in the hobby and way to learn about how the plants behave and grow, how to train them, and so forth.