Its lighter than wood. Not bad, But you will have to brace it more. It isn't as sturdy so the frame will be the load bearer.
Channeled corners, routered or cut with a dado blade so the panels slide in then caulked or hot glued. My cab now is 5'. not enough.
You could screw or nail it conventionally to a frame, but then you have the frame inside taking space, Channeled puts as much of the bracing outside as you want. 2"x 2" stock would work nicely. I want hollow walls to put ducts that hold activated charcoal with the draw fan under a sub floor