Mango contains myrcene, an essential oil that is part of a class of compounds called terpenes. Terpenes are responsible for the strong smell of cannabis and some of its effects. Different varieties of cannabis (and mangoes) produce more myrcene varieties than others. Myrcene is definitely synergistic with THC, the primary psychoactive constituent of cannabis.
Myrcene is believed to be responsible for sedative “couch lock” effect of wide-leafleted “indica” varieties of high-THC cannabis. Dried flowers of these indicas can contain nearly 2 percent myrcene. It is incorrect to state that myrcene is linked to the euphoric psychoactivity of cannabis, as myrcene is more responsible for the “stone,” rather than euphoria.
The bad news is that orally administered myrcene is not likely to reach your bloodstream, since it’s not easy for it to be absorbed through the gut and survive liver metabolism. Plants evolved terpenes like myrcene, in part to discourage grazing animals and attract some insects and repel others. We evolved the ability not be poisoned by these terpenes, by limiting their ability to be metabolized.