I'm focusing on ventilation / air flow paths because it can have the biggest impact on later equipment needs and operating energy costs.
Just trying to avoid the 'build a great grow closet...then have to move in a dehumidifier...then an a/c unit to offset...then pay the bills for both of them in addition to lights'.
Not sure of your floorplan, but something like this with dampers would probably give you the most flexibility - if you happened to need it:
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