For personal grows I can't imagine the electrical cost for running 250w for instance being significantly different running 20/4 over 12/12. Obviously energy cost would determine that, but I live in an area of the country with fairly high electric costs and I did not notice a big increase with my 240w blackstar, 4bulb t5, circulation fan, exhaust fan running 24hr. Then when i reduced the light to 12/12 for a photo, still no big change. It could have been as much as $10 a month difference, but I doubt it.
Now if you are talking about a big grow room with some serious HPS and the supporting fans and ac, yeah that would make a difference. But if someone were seriously thinking along those lines, they need to do real number crunching on their own. Because just asking for advice from a forum is not going to break things down by dollars & cents. Then your talking a business and you should have a business plan laying out all your costs & expenses anyway. And every area has their own nuances that could have a big effect on the bottom line.