Would you do anything to this?

What problem do you see that would be corrected by defoliating? I would only remove leaves substantially blocking buds forming (but I don't see any in the photo). Why mess with a plant that looks perfectly healthy, such as this one? Maybe if you see a need, pluck a few of the very bottom leaves for better air circulation.

But there are others who routinely remove a lot or even all but a few fan leaves.
 
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I see plenty that I'd pull, to force the energy into the buds.

I'd clip the leaves that shadow other buds, also leaves that go inwards. Try to pen up the center more.

Your grow bag has eyelets for cord that can be used to pull branches out and down.
 
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