Why Your Weed Smells. Terpenoids.

I've noticed there is nothing on the forum about terpenoids so thought I would throw up a little info from the web.


Have you ever wondered how the strain Blue Dream can smell so similar to fresh blueberry doughnuts? Or how a sniff of the K.O. Kali-O seems to burst with citrus just like a California Orange? Yes, it is the cannabis. More specifically, what you are really smelling (and tasting) are terpenes.

Terpenes are a large and varied class of hydrocarbons (made up of hydrogen and carbon), produced by a wide variety of plants and also, some insects. Terpenes are referred to as terpenoids when denatured by oxidation (like being dried and cured) or chemically altered by some rearrangement of the carbon skeleton. They are the main component of any plant resin or essential oils and play many important roles in the plant kingdom- from deterring insect predation, protection from environmental stresses and vitally, as chemical building blocks for more complex molecules, like cannabinoids, certain hormones, vitamins (Vitamin A), pigments and sterols.

Terpenoids contribute to the scent of eucalyptus, the flavors of cinnamon, cloves, and ginger, and the color of yellow flowers. Well-known terpenoids include citral, menthol, Salvinorin A in the plant Salvia divinorum and also cannabinoids.

Plant terpenoids are used extensively for their aromatic qualities. They play a role in traditional herbal remedies and are currently under investigation for antibacterial, anti-neoplastic (cancer halting), and other pharmaceutical functions.

We are all familiar with cannabis as medicine or as a recreational drug, but the more subtle aspect of it being an aromatic plant goes too often unsaid. The herbs we use in our kitchen are considered aromatic plants because they contain a particular terpene profile that gives a distinctive flavor. Cannabis is so complex from this point of view that the possible terpene combinations are endless, creating a broad spectrum of aromas and flavors.

Many plant terpenes act synergistically with other terpenes and some serve to either catalyze or inhibit formation of other compounds within a plant. For example, understanding the role of certain terpenes will allow scientists to manipulate cannabinoids to desired ratios. Some terpenes are said to modulate the physiological and psychoactive effects of cannabis.

Cannabis ususally contains a significant amount of a terpene called beta-caryophyllene (BCP), which contributes to the aroma and flavor. Studies show that this terpene, also found in other legal herbs, spices and food plants (it contributes to the spiciness of black pepper), activates the CB2 receptor and acts as a non-psychoactive anti-inflammatory. Because it binds to a cannabinoid receptor, it is considered a cannabinoid and since the widespread natural plant product beta-caryophyllene is an FDA approved food additive and ingested daily with food, it is the first dietary cannabinoid. Whether this compound is able to modulate inflammatory processes in humans via the endocannabinoid system is yet unknown.

Additional research is needed into how these legal compounds participate in providing medicinal properties to marijuana. However, unjust Schedule I classification makes it illegal to extract perfectly legal compounds from the cannabis plant in a lab.

The Green House Seed Company based in Holland, has isolated 16 of the most characteristic and recognizable terpenes, the one�s involved in the distinctive flavor of any strain. For example, Alpha-Pinene is an organic compound found in the oils of many species of pine trees. It is also found in the essential oil of rosemary and present in the oil extracted from the eucalyptus tree. This terpene was also found at the highest level in the Super Silver Haze when analyzed by the Green House Seed company. So, if you like pine-tree smelling and tasting cannabis, you might respond well to this strain.

Myrcene, or β-myrcene, is a monoterpene and an organic compound. It is obtained from the essential oil of various plants: bay, mango, myrcia (from which is gets its name) and cannabis, but not hemp. Its odor is described as clove-like, earthy, green-vegetative, citrus, and fruity with tropical mango and minty nuances.

In volume III of the Big book of Buds, Ed Rosenthal states that the presence of Myrcene is an important factor in the quality and enjoyment of the high from smoking certain Cannabis strains, particularly those strains that came from tropical climates � namely Sativas. Myrcene is also one of the most important chemicals used in the perfumery industry because of its pleasant odor. Although it is rarely used directly, it acts as an intermediate for the preparation of flavor and fragrance chemicals such as menthol and geraniol.

Limonene is another terpene. It is a colourless liquid at room temperatures with an extremely strong smell of oranges. According to an article in Cannabis Science, limonene can induce �relaxation� and has it�s own unique pharmacology. It takes its name from the lemon because lemon and other citrus fruits contain high quantities of this compound, which is responsible for much of their smell. Interestingly, it has been considered as a bio-fuel as it is combustible when pure. It is also present in many cannabis strains.

There are over 120 kinds of terpenes in cannabis, some only in trace amounts with others in double-digit percentage. Being able to measure these volatile compounds before and after a breeding experiment will offer the cannabis scientist endless opportunities for developing new flavors by basing breeding decisions on real analytical data.

Examples of some common Terpenes found in Cannabis:
-Borneol- menthol, camphor, pine, woody. Can be easily converted into menthol. Found in Cinnamon and Wormwood. It is considered a "calming sedative" in Chinese medicine. It is directed for fatigue, recovery from illness and stress.
-Caryophyllene - spicy, sweet, woody, clove, camphor, peppery. Found in black pepper(15-25%), clove(10-20%) and cotton(15-25%). It binds weakly to CB2 receptor. As a topical it is one of the constituents of clove oil, an anti-inflammatory and analgesic treatment for toothache. In high amounts, it�s a calcium and potassium ion channel blocker. As a result, it impedes the pressure exerted by heart muscles. Since THC does not have a smell, drug dogs are trained to find one, very smelly molecule called Caryophyllene-epoxide!
-Cineole/Eucalyptol- spicy, camphor, refreshing, minty. Found in rosemary, eucalyptus. It is used to increase circulation, pain relief and easily crosses the blood-brain-barrier to trigger fast olfactory reaction. Eucalyptus oil is considered centering, balancing and stimulating. It is possibly the stimulating and thought provoking part of the cannabis smoke stream.
-Delta3Carene- sweet, pine, cedar, woodsy, pungent. A constituent of rosemary, pine and cedar resin. In aroma therapy, cypress oil, high in D-3-carene, is used to dry excess fluids, tears, running noses, excess menstrual flow and perspiration. It may contribute to the dry eye and mouth experienced by some marijuana users.
-Limonene- citrus (orange, tangerine, lemon, and grapefruit), rosemary, juniper, peppermint. Repulsive to predators. Found in the rinds of many fruits and flowers. With the presence of other certain terpenes, Limonene can be an anti-bacterial, anti-fungal, anti-depressant and anti- carcinogen. It can synergistically promote the absorption of other terpenes by quickly penetrating cell membranes. The result can be increased systolic blood pressure. Since Limonene is such a potent anti-fungal and anti-cancer agent, it is thought to protect against aspergillus fungi and carcinogens found in cannabis smoke streams!
-Linolool- floral (spring flowers), lily, citrus and candied spice. Possesses anti-anxiety and sedative properties (also in lavender).
-Myrcene � clove like, earthy, green-vegetative, citrus, fruity with tropical mango and minty nuances. The most prevalent terpene found in most varieties of marijuana, it is also present in high amounts in Mangos, hops, lemon grass, East Indian bay tree, verbena and Mercia. Myrcene is one of the most important chemicals used in the perfumery industry. Because of its pleasant odor, it is occasionally used directly. It�s a building block for menthol, citronella, and geraniol. It possesses antimicrobial, antiseptic, analgesic, antioxidant, anti-carcinogen, anti depressant, anti-inflammatory, and muscle relaxing effects. Myrcene affects the permeability of the cell membranes, allowing more THC to reach brain cells.
-Pinene- Alpha: pine needles, rosemary Beta: dill, parsley, rosemary, basil, yarrow, rose, hops, the familiar odor associated with pine trees and their resins. It is the major component in turpentine and is found in many other plant essential oils including rosemary, sage, and eucalyptus. Pinene can increase mental focus and energy, as well as act as an expectorant, bronchodilator (the smoke seems to expand in your lungs), and topical antiseptic. It easily crosses the blood-brain barrier where it inhibits activity of acetylcholinesterase, which destroys acetylcholine, an information transfer molecule, resulting in better memory. It may counteract THC's activity, which leads to low acetylcholine levels. Largely due to the presence of pinene, rosemary and sage are both considered "memory plants." Concoctions made from their leaves have been used for thousands of years in traditional medicine to retain and restore memory.
-Pulegone- mint, camphor, rosemary, candy. It is implicated in liver damage in very high dosages. It is found in tiny quantities in marijuana. Pulegone is an acetylcholinesterase inhibitor. That is, it stops the action of the protein that destroys acetylcholine, which is used by the brain to store memories.
-Sabinene - Found in oak trees, tea tree oil, black pepper and is a major constituent of carrot seed oil.
-Terpineol- floral, lilac, citrus, apple/orange blossoms, lime. It is a minor constituent of many plant essential oils. It is used in perfumes and soaps for fragrance. It reduces physical motility 45% in lab rat tests� Couch-lock effect?"

Here are the links....http://berkeleypatientscare.com/2010/10/08/terpenes-terpenoids-and-cannabis/


http://terpenes.weebly.com/
 
Hi Aunty! :tiphat: Thanks for the tip on Ed's new book, ...That I'm gonna check out! It's funny that this thread popped up for me just now, as I have half a dozen small piles of kief drying out, and filling the room with various enticing aromas! I'm curious as to how you tune-up your Dragon Masters' noses :brow:..... Oh yeah, I have some very interesting orchid flower pics of a particular species that had me thinking of you; it's more common name is the Antelope Orchid, because it has 2 narrow spiral petals that point straight up resembling horns, but me and my old boss always called it the Dragon's head orchid! .... a more accurate description, IMO... I'll send you some pics via PM later, okay? Thanks Aunty!

{ LOL! okay, plan C...}
Hi Aunty! I posted those pics here: https://www.autoflower.org/f16/pictures-rebs-2993-8.html#post439420
...hope you enjoy stylez rasta smoke
 
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Amazing information, Tang! Great read.

I was trying to classify the exact flavor of Salvia on that spectrum, but I had trouble locating the taste that I would describe as "Vibrating Balloons" :rofl:
 
The Major Terpenes of Cannabis Resin and Their Effects

Borneol – Borneol is a major component of cannabis resin that can also be found in cinnamon and wormwood (Artemesia spp). In Chinese medicine herbs containing borneol are recommended for fatigue and overstress. Borneal is mentioned to be a calming sedative.

Corryphyllene – Corryphyllene is a major component of cannabis resin that can also be found in black pepper and cloves. It is a fairly weak agonist of the type 2 cannibinoid receptors (cb2). As a constituent of a salve or lotion corphyllene is an effective anti- inflammatory and analgesic. Drug dogs are trained to specifically sniff out corphyllene epoxide, a similar compound produced only by cannabis.

Cineole/eucalyptol – Cineole/eucalyptol content is quite variable across varieties of Cannabis, but is often a major component of the essential oil. It is also found in rosemary and eucalyptus and is used to increase circulation, and reduce pain and swelling when applied topically. It readily crosses the blood/brain barrier, possibly helping cannabinoids to cross more readily as well. The effects of cineole, when combined with oral or smoked Cannabis, are reported as being very uplifting, noticeably increasing mental and physical energy. This terpene,or others like it, may be responsible for the reported difference in effect between indica and sativa strains with a similar cannibinoid profile.

Limonene – Found in cannabis resin as well as tropical fruit rinds, Limonine is an anti-bacterial, anti fungal and anti cancer agent. Currently undergoing trials for use as an anti depressant, it is also known to increase the absorption of other terpenes by making cell membranes more permeable. The presence of this anti fungal agent may be helpful in protecting against Aspergillus infection in those with compromised immunity when using spoiled or poorly cured marijuana. Limonine is currently in trials to study its ability to prevent breast cancer formation.

Delta-3-Carene – A component of cannabis, rosemary, pine, and cedar resin. Aromatherapy oils that contain high levels of delta3carene are used to dry excess fluids from the eyes, nose, or mouth. It is thought to be at least partially responsible for the dry mouth and eye problems that are common side effects of the use of cannabis.

Linalool – This major component of cannabis and lavender oils is believed to possess anti anxiety and sedative properties. Strains that are high in linalool and similar compounds may be particularly beneficial for patients who experience insomnia when consuming Cannabis.

Myrcene – Significant concentrations of Myrcene are present in cannabis resin. It is also found in mango, hops, lemon grass, East Indian bay tree, and verbena. Because of its appealing fragrance, myrcene is used in the perfume industry. It has a similar modulating effect on the binding of Cannibinoid agonist drugs as Cannabidiol, possibly reducing effects of Cannabis resin that are found to be unpleasant for some medical users. It has anti microbial, anti septic, analgesic, anti oxidant, anti carcinogen and anti-inflammatory properties. It has shown some promise when used as an anti depressant, or as an additive to other anti depressant drugs and is also used in massage therapy as a muscle relaxer.

Terpineol – Minor component of Cannabis resin, used extensively in the perfume industry. Interestingly this terpene decreases motility of lab rats by 45 percent, this observation coupled with the fact that this is a terpene produced primarily in Cannabis indica plants indicates terpineol could play a role in decreased motility sometimes referred to as “couch lock”.



Terpenes May Improve Effectiveness Of Medical Marijuana

Terpenes Influence The Synergy Effect Of Cannabis
As we know, science has identified and characterized the molecular structure of around 20,000 terpenes, which makes it the largest category of plant chemicals. These aromatic compounds are found in the essential oils of plants and flowers, and plenty of studies have been done on their effects.
Of the 20,000 identified terpenes, there have been more than 120 found in cannabis. Only a few of them appear in high concentrations, but they have been found to have a number of benefits. A few of these effects are covered in our terpenoid article, but recent research has suggested an “entourage effect” as well. In his 2011 study “Taming THC,” Ethan Russo, from GW Pharmaceuticals, discussed the interaction between terpenes and cannabinoids.

Terpenes May Reduce THC-Induced Anxiety

“Citrus fruits (high in limonene) were used as a ‘cannabis antidote’ in 10th century Persia.”
For years, tetrahydrocannabinol (THC) was the only cannabinoid investigated for its medicinal value, and we know it has the potential to cause anxiety in some patients. However, certain terpenes in cannabis, like Linalool, have been found to counter the anxiety.

In fact, Russo points out that terpenes likely played a role in a number of ancient antidotes for the less desirable effects of THC. For instance, citrus fruits (high in limonene) were used as a “cannabis antidote” in 10th century Persia. Other ancient antidotes include calamus plant roots and pine nuts (high in pinene), as well as black pepper (high in caryophyllene and myrcene).

Terpenes And Cannabinoids Can Work Together

Terpenoids can be used for more than countering THC-induced anxiety. Russo discussed interactions to treat a number of issues including: pain, inflammation, depression, addiction, epilepsy, cancer, and infections.

Russo believes pinene would be useful in the treatment of MRSA. Cannabigerol (CBG) is a potent MRSA inhibitor, and can be found with small amounts of THC. Because of this Russo suggests a whole-plant extract, high in CBG and pinene, which was found to have its own anti-MRSA qualities in 2010.
“Combining terpenoids with a CBD-rich extract may help treat the wide-ranging effects of Alzheimer’s disease.”

Terpenes could also aid in Alzheimer’s treatment with cannabidiol (CBD). Linalool, which is prominent in lavender, helps counter stress and anxiety. Limonene is commonly used in aromatherapy to improve mood, and pinene is known to promote alertness and memory retention. Combining these terpenoids with a CBD-rich extract may help treat the wide-ranging effects of Alzheimer’s disease.

Another interaction that Russo highlighted could have benefits for addiction treatment. An essential oil made from black pepper reduced nicotine cravings in cigarette smokers. Interestingly enough, black pepper essential oils are high in myrcene, pinene, and caryophyllene, all of which can be found in cannabis.
Caryophyllene is interesting because it directly stimulates the CB2 receptors throughout the body. As we know, CB2 agonists prevent the release of dopamine, which is related to addiction. This, in combination with the use of CBD for opiate withdrawal, suggests that cannabis with caryophyllene could have a variety of rehabilitative benefits.

“K”, like multiple growers on online forums, believes that a number of variables (lighting, soil composition, nutrients, etc.) can influence terpene production. If growers are able to influence the production of specific terpenes, they could improve their product’s effectiveness.

Terpenes Can Improve Medical Marijuana, Infused Products

It’s been reported that certain terpenes dilate capillaries in the lungs. Logic tells us that this would be useful in the case of smoked or vaporized cannabis. Dilated capillaries would enable beneficial cannabinoids to enter the bloodstream easier. This certainly could be useful for growers who know how their crops will be ingested, and in the production of cannabis concentrates.
In fact, a number of concentrate makers enhance their finished product with pure terpenes. This is typically done for added flavor, as the more volatile terpenes can be lost during the extraction process. However, infusing concentrates with a specific terpene for added effect would be equally beneficial. For instance, pinene is a bronchodilator, which could benefit asthma patients.

In fact, similar processes already exist. According to Jeff Raber, founder of The Werc Shop, a lab-testing facility in Los Angeles, they are able to infuse concentrates with the terpenes lost. “Based on the terpene-profile of each strain,” he added, “we can recreate as much of the whole plant component as possible.”
One step further, K believes terpene-rich extracts could play a major role in the future of medical marijuana. He points out that some patients might want the terpene-related flavor and relief, without the high from THC.
Another potential application of terpenes could benefit users of medicated topicals. Nerolidol, a sedative terpene, is a known skin penetrant. Therefore, it could aid in cannabinoid absorption if infused in topicals.

The benefits of terpenes are widely recognized, but they just now are being explored by experts in the cannabis industry. As Ethan Russo pointed out, terpenes may influence a number of cannabis’ benefits. Their interaction with cannabinoids often impacts the effectiveness of medical marijuana strains and products, and could be used to facilitate a better overall experience.
 
Nice post Tang, interesting info there.
 
All descriptions of the effects of terpenes make frequent use of the word "may."
That is a weak word that contains no certainty, and can also mean "might not."
It's the same word herbal supplement sellers use to peddle supplements of questionable value.
 
I’ve just had a good read off it, I’m really intrested in a the terpene values and can certainly see myself basing future grows, and comparing strain terpene profile with the information above too find a perfect strain.


Limonene terpene is quite i tresting yoo me, so I’m going too look into super lemon haze


Also dna seeds have a strain called tangie which has a massive terpen value

Also last off all a strain called chocolate mint og has a good terpene profile

So what I’m trying too say thease 3 are my biggest candidates, studied
 

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