From my experience, Yes.
I had a really good looking female, so I dusted her, a couple days later the plant toppled and the main stem folded in half, I took some tape and wrapped her up, it didn't grow vertically, but bushed out and ended up with a ton of seeds. It also had some PH issues.
A few months later, I started the seeds with no problems at all, the female plants were nice and produced some really good meds.
Hope this helps. Aloha