Thanks buddy!! I hope it turns out alright.
I wanted to show this that I stole it from
@Lady Lollipops in Live stoner chat. thought this had a good pairing with an agro vid. neat article too.Thanks
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COVID And Cannabinoids
The majority of people who suffer severe coronavirus symptoms develop a condition called Acute Respiratory Distress Syndrome (ARDS). As we reported in an
earlier blog post, this is caused by the immune system going into overdrive and releasing a glut of inflammatory compounds called cytokines, resulting in a “cytokine storm” in the lungs.
Since the start of the pandemic, researchers have already discovered that THC treatment prevents this cytokine storm from occurring in mice with ARDS, leading to a 100 percent survival rate. On top of that, a new study was published last month indicating that CBD also downregulates the production of cytokines in the lungs of mice that had been infected with a virus that mimics the effects of COVID
[ii].
While this is obviously excellent news, researchers had until now been unable to explain how these cannabinoids inhibit the release of cytokines in the presence of ARDS. Fortunately, the key now appears to have been found, with apelin being the magic ingredient.
What Is Apelin?
Apelin is produced in the lungs, heart, brain, fat tissue and blood, and is released in response to extreme changes in inflammation or blood pressure. For instance, when a lung infection occurs, apelin levels tend to go up in the surrounding cells in order to make sure that no cytokine storm occurs and everything continues to work as it should. In this way, it prevents ARDS from developing, or at the very least initiates a speedy recovery from ARDS.
In the new study, researchers infected mice with a COVID-like virus before measuring apelin levels in their lungs. Ordinarily, apelin concentrations would be expected to soar in response to such an infection, yet the study authors noted that the opposite occurred, as levels of the peptide plummeted to virtually zero.
This would seem to suggest that coronavirus somehow inhibits the production of apelin in the lungs, which would explain why it is so deadly.
However, after treating infected mice with CBD, apelin levels were restored. As a consequence, ARDS symptoms in these mice were reduced, while a closer examination revealed that the immune response of these rodents had been normalised along with oxygen flow and tissue damage in the lungs. In contrast, mice that had not received the cannabinoid saw no improvement in their condition.
All in all, these results suggest that CBD’s ability to stem the release of cytokines and reduce inflammation in the lungs is mediated by apelin, which for some reason is inhibited by coronavirus but restored following treatment with the cannabinoid.
Research is now ongoing to discover how this can be applied to humans suffering from COVID-19 and other ARDS-related conditions.
and this one from
@Mossy nice info
Researchers from the Dental College of Georgia say that CBD appears to reduce the ‘cytokine storm’ that damages the lungs of patients with Covid-19
www.mirror.co.uk
