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This is just from personal experience. I don't smoke I only eat or vape so I have to rely on a group of super taster chef friends I have. They are very critical of the samples I provide them. When I grew in organic live soil I did not flush and never had a single complaint. Then when I moved to hydro DWC I did not flush the first plants and everyone complained. So it was obvious I needed to do some thing. I now use a 3 day flush with Advanced Nutrients Flawless Finish in my rock wool grows and the last DWC I did. The complaints went away - not one. I do not flush until the plant is ready for harvest so it does not need to grow anymore. This is just my personal experience your mileage may vary.