Yes. I do both without issue. I take two clones prior to flower. I spray one, clone and pollinate the other. The timing won't matter much with the clones because they are strictly for seeds.. So you can let them go much longer than you would a normal plant. The process is called "selfing".. This is what "S1" means.. Like Gelato 33 for example. There were never reg seeds made of it because it was a clone only. SJ used selfing to make and sell the Gelato 33 S1's.