CBD numbers and measurements

tag60435

tag60435

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My wife was recently diagnosed with Multiple Myeloma, an incurable bone cancer when treated with conventional drug regimens. She only has a 30% life expectancy 10 years from now. Recent research in Italy has again shown CBD to be effective at KILLING multiple Myeloma cells. I live in Texas so no marijuana is legal, and I certainly don't have access to any dispensaries. In the limited research that I have done, I am finding that most seed suppliers and even most breeders websites don't really give CBD%. Lots of sites will tell you THC% but it is fairly rare for CBD and CBN. Does someone have a location of reputable quality information concerning CBD numbers by strain? This would really be a big help in my quest for knowledge to help my wife.

Thanks in advance for any help
 
Very sorry to hear about this, but welcome to the fun family over here :) You'll want to read up all you can on "RSO" (Rick Simpson Oil), and some experts here can help. At this point, CBD is just recently been given more spotlight (demand) and now breeders are struggling to get solid CBD strains out there fast enough lol. Another issue with strains from seed (as opposed to grown from clones) is that numbers can vary widely between plants :( this is the genotype / phenotype effect. So the CBD numbers can be hard to trust. It'll take a good bit of web research. Med Gom 1.0 auto is a CBD autoflowering plant, with numbers between 4% and 14%. But there are many more photoperiod CBD strains, I think Dutch Passion has a couple new ones, and then there's anything by CBD Crew. I don't know of a particular list though, although that would be great haha.
 
Welcome,tag :) Yes, that is some heavy news to bear, my friend. I send every good thought/vibe/prayer to you and your Mrs. I'm a medical grower in Maine, and your story repeats itself here, far too often. Anthropolis gives good info, and I too recommend doing some searches on Rick Simpson Oil (This'll get you there, for a start- http://phoenixtears.ca/)
If I were in your situation, I would consider going to Colorado to procure RS Oil, and any number of other high CBD solutions. The internet is full of stories of just such a pilgrimage. Its not as simple as driving into Denver, and you're set up in the hour. But, there are ways to do so, and a ready supply of those precious CBDs.
As for strains, I am running a grow test of a Dutch Passion high CBD strain, that is bred to have a very high CBD %. They have several great strains for CBD needs- CBD Skunk Haze is in my seed locker, and this new strain (not released yet, but soon) will likely raise the bar for CBD % and 1:1 CBD:THC strains.
My heart goes out to you folks. If I can be of assistance, look me up here :)
Waxi
 
Compendium of High CBD Medical Cannabis Seeds

Sorry to hear of your troubles. Please read the below information.

I have taken this from another website. Please refer here for the original post link http://www.420magazine.com/forums/m...h-cbd-medical-cannabis-seeds.html#post2294314

"
Caveat: I am not a medical doctor, nor do I play one on TV. I am writing from my experience and research. However, according to multiple studies in the US National Library of Medicine National Institutes of Health, CBDs have proven medical applications in treating chronic pain, epilepsy, neuropsychiatric, and psychiatric disorders. (i.e.: Cannabidiol: pharmacology and potential therapeutic role in epileps... - PubMed - NCBI)

Parents: For treating seizure disorders in children, very low THC strains with a high CBD profile is recommended. Newly released Thunderstruck by Sin City is commercially available in seed form and rivals Charlotte's Web.

Cancer: While this is not a cancer treatment list, for cancer applications, try high THC strains of at least 15% THC with at least 5% CBD to make the most of cannabis' synergistic curative properties, tumor reduction, appetite increase, pain relief, stress and anxiety relief. (EG: Blue Blood) High THC buds cut with high CBD buds is another option.

I built this list of high CBD strains while writing my CBD Medical Cannabis Brew thread. I wasn't expecting the list to get so huge. Hence, I decided to give the list its own thread so others could contribute and help with corrections. I've only included high CBD strains which have at least 5% CBD and excluded 1-5% CBD strains and strains that I could not find percentages on because the definition of high CBD fluctuates and could mean anything. This is a seed only list as some popular CBD strains like Charlotte's Web may not be commercially available in seed form.

The list is divided the way it is to help growers decide which strains work best for their growing conditions. Bushy photo period strains tend to be more indica dominant. Mixed traits photo period strains can have phenotypes that pull either indica or sativa growth patterns or have wild CBD fluctuations and should be tested professionally for phenotype quality. Tall photo period strains tend to pull more sativa growth patterns. Autoflowering strains tend to have ruderalis growth patterns.

5%+ CBD Bushy Photo Period Strains:

  • TGA Subcool Pennywise Regular Seeds | THC: 12-15% | CBD: 12-15%
  • Medicann Blue Blood Feminised Seeds | THC: 15-20% | CBD: 10%
  • Paradise Durga Mata II CBD Feminised Seeds | THC: 7% | CBD: 8.5%
  • Barneys CBD Critical Cure Feminised Seeds | THC: 5.5% | CBD: 8%
  • Dinafem Feminised Critical Mass CBD Seeds | THC: 6-8% | CBD: 6-8%
  • Dutch Passion CBD Kush Feminised Seeds | THC: 7% | CBD: 7%
  • Barneys CBD Blue Shark Feminised Seeds | THC: 6.5% | CBD: 6.5%
  • Dinafem Feminised Shark Shock CBD Seeds | THC: 6% | CBD: 6%
  • CBD Crew Shark Shock Feminised Seeds | THC: 6% | CBD: 6%
  • CBD Crew Sweet N Sour Widow Seeds | THC: 5% | CBD: 5%

5%+ CBD Mixed Traits Photo Period Strains:

  • Resin Cannatonic Feminised Seeds | THC: 1.16-25% | CBD: .33-20% (wild fluctuations)
  • BC Bud Depot CBD God Regular Seeds | THC: 4% | CBD: 4-16% (wild fluctuations)
  • CBD Crew Critical Mass Feminised Seeds | THC: 5% | CBD: 5%

5%+ CBD Tall Photo Period Strains:

  • Sin City Thunderstruck Feminised Seeds | THC: .1-2% | CBD: 16-22%
  • Sin City Treasure Island Feminised Seeds | THC: 2-4% | CBD: 8-16%
  • Sin City HarleSin Feminised Seeds | THC: 5-8% | CBD: 10-15%
  • BC Bud Depot Harlequin Bx4 Regular Seeds |THC: 7-12% | CBD: 7-12%
  • CBD Crew Mango Haze Feminised Seeds | THC: 6-8% | CBD: 8-10%
  • CBD Crew Medi Haze Feminised Seeds | THC: 4% | CBD: 8%
  • Dutch Passion ComPassion Feminised Seeds | THC: 6% | CBD: 6%
  • CBD Crew Skunk Haze Feminised Seeds | THC: 5% | CBD: 5%
  • Dutch Passion CBD Skunkhaze Feminised Seeds | THC: 5% | CBD: 5%

5%+ CBD Autoflowering Strains:

  • CBD Crew & Grass-O-Matic Med GOM Auto 1.0 Feminised Autoflowering Seeds | THC: 4-10% | CBD: 15% "
 
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Whoa, there's a list! How awesome! I predict it'll be growing quite a bit as CBD gains traction and interest. An important thing to note about history, is the point that once upon a time long ago, CBD was more prevalent in common strains. Human selective breeding has accidentally bred out CBD in search of more pure THC. Now all of the sudden, we're realizing the importance, and breeding it back in to select strains. Anyways, as mentioned above, for cancer I remember reading a lot about the good ratio being close to 1:1 CBD:THC if possible. Of course this means some of the buzz too.
 
:welcome:to AFN!

Sorry to hear of your wife's illness.
Here is a thread to make CBD oil


Curcumim has also been an effective treatment

http://www.myelomabeacon.com/news/2...romising-still-awaiting-more-clinical-evidenc
Curcumin And Multiple Myeloma: Preclinical And Early Clinical Studies Are Promising; Still Awaiting More Clinical Evidence

by Francie Diep
Published: Feb 17, 2010 12:59 pm

Curcumin has been garnering increased attention as a potential anticancer treatment. It is the major active compound in turmeric, a popular Indian spice made from the rhizomes, or underground stalks, of a plant in the ginger family.
In multiple myeloma and the precursor condition monoclonal gammopathy of undetermined significance (MGUS), cell culture studies and one animal study have shown that curcumin can kill cancer cells and prevent them from multiplying. The Beacon also found two early-stage clinical trials studying curcumin’s effects in people with multiple myeloma and MGUS. Their results were promising, but not definitive.

All of the studies discussed here suggest that curcumin is relatively safe.
In India, where turmeric is used extensively in cooking, the average person consumes 60 to 200 mg of curcumin through his daily diet, according to the National Institutes of Health’s Medline Plus.
Studies in myeloma cells and in mice
Several recent lab studies have demonstrated that curcumin kills myeloma cells and increases the effects of conventional drug therapy:

  • At Zhongnan Hospital of Wuhan University in Wuhan, China, scientists found that the addition of curcumin to melphalan (Alkeran) reduced myeloma cell proliferation, increased myeloma cell death, and increased the concentration of melphalan in cells. They found that curcumin reduces the production of a protein that helps tumor cells repair damaged DNA. The journal Annals of Hematology(abstract) published their research in September.
  • M. D. Anderson Cancer Center scientists in Houston found that curcumin slowed down the growth of multiple myeloma cells that are resistant to dexamethasone (Decadron), doxorubicin (Adriamycin), and melphalan. It also enhanced the effects of thalidomide (Thalomid) and Velcade (bortezomib). By performing experiments on mice, the researchers confirmed curcumin’s ability to augment the effect of Velcade. They published their findings in the journal Molecular Cancer Therapeutics (abstract) in April.
  • Two older studies by the same M. D. Anderson researchers also found evidence of curcumin’s ability to kill myeloma cells, reduce or prevent myeloma cell proliferation, and enhance the effectiveness of conventional drugs. These studies appeared in the journals Blood and The Journal of Immunology(PDF) in 2003.
Clinical trials
Clinical trials on curcumin’s effects on people with multiple myeloma or MGUS have also been promising, but thus far the evidence is limited to small, preliminary studies. The Myeloma Beacon found two such studies.

  • In Sydney, Australia, one trial examined 26 people with MGUS who either took 4 g of curcumin by mouth every day for three months, then switched to a placebo, or took the placebo first for three months, then switched to the curcumin treatment. The researchers found that during the placebo phase, study participants’ abnormal protein levels either stayed steady or increased, while during the curcumin phase, participants’ protein levels either stayed steady or decreased. The curcumin treatment tended to work better for participants who had higher starting levels of abnormal protein in their serum (20 g/L or more). Two participants had to drop out of the study early because of abdominal cramping and diarrhea. The research was published in the journal Clinical Cancer Research (abstract) in September.
  • In the same issue of the Clinical Cancer Research journal, Dr. S. Vincent Rajkumar of the Mayo Clinic published a commentary (abstract) on the study. Rajkumar wrote that the study uses “nonstandard response criteria” to evaluate the participants’ responses to the curcumin therapy, and the results therefore will not affect how doctors treat people with MGUS. He added that curcumin needs further research.
  • In a Phase 1/2 clinical trial, M. D. Anderson researchers examined curcumin’s effects on two molecular pathways known to cause tumor cells to grow and spread. Twenty-nine people with multiple myeloma were divided into two groups – one group taking curcumin alone in increasing doses and the other group taking curcumin plus Bioperine, a compound from black pepper, also in increasing doses. The researchers found that curcumin reduced the growth and spread of myeloma cells, but participants did not show any statistically significant responses. Researchers reported that their study participants did not feel any significant side effects. They presented their findings at the American Society of Hematology’s (abstract) 2007 Annual Meeting.
Due to the insufficient number of clinical trials, Medline Plus gives the use of curcumin for cancer a “C” grade, which means there is “unclear scientific evidence for this use.”
Taking curcumin
Nevertheless, some myeloma experts are enthusiastic about using curcumin to treat multiple myeloma and MGUS. Because it works against many steps in cancer, curcumin is “ideal” to use against multiple myeloma, said Bharat Aggarwal, University of Texas biochemistry professor and principal investigator for many of the M. D. Anderson curcumin studies, in an International Myeloma Foundation webcast. He widely promotes the therapeutic use of curcumin through interviews, a Web site, and a book.
Margaret Graziano, diagnosed with MGUS in 1999 and smoldering myeloma in 2005, has been taking curcumin for four years. She decided to try curcumin when her myeloma markers were worsening and her hematologist suggested she start chemotherapy.
She told her doctor she wanted to try taking curcumin for eight weeks before starting any chemotherapy. Her doctor agreed to delay treatment. After the eight weeks were up, her myeloma markers had improved to the point that her diagnosis returned to smoldering, with no need for chemotherapy. She has been considered a smoldering myelma patient ever since.
“I am almost one hundred percent positive that, had I not taken this yellow powder, I would have progressed to active myeloma by now. Just a gut feeling, though,” wrote Graziano, who takes curcumin supplements daily, in an email to The Myeloma Beacon. Her hematologist knows about the supplements she takes and supports her, she added.
Those who decide to try curcumin should keep in mind that at this time, it is regulated by the Food and Drug Administration as a dietary supplement. Companies who make it are responsible for ensuring its safety, but do not need to register with the FDA.
After a supplement is on the market, the FDA monitors its safety but not its effectiveness. There is not yet any medical standard for how much curcumin patients should take, or how often. Trials in multiple myeloma and in other cancers have tested varying doses.
Patients can read tips on how to choose supplements on the FDA’s Web site. They can also find information on potential side effects and drug interactions on Medline.
Multiple myeloma patients may have to wait a while before the efficacy of curcumin is studied according to modern medicine’s standards. Meanwhile, patients have numerous preclinical and early clinical trials and other resources to consider before choosing whether to take curcumin supplements. Patients should always consult their physicians before taking any supplements.
 
tag60435 said:
My wife was recently diagnosed with Multiple Myeloma, an incurable bone cancer when treated with conventional drug regimens. She only has a 30% life expectancy 10 years from now. Recent research in Italy has again shown CBD to be effective at KILLING multiple Myeloma cells. I live in Texas so no marijuana is legal, and I certainly don't have access to any dispensaries. In the limited research that I have done, I am finding that most seed suppliers and even most breeders websites don't really give CBD%. Lots of sites will tell you THC% but it is fairly rare for CBD and CBN. Does someone have a location of reputable quality information concerning CBD numbers by strain? This would really be a big help in my quest for knowledge to help my wife.

Thanks in advance for any help
Click to expand...

Hi Tag, welcome to AFN, wish it was under better circumstances.

The RSO protocol as originally developed by Rick uses high THC strains, it takes about pound of good quality bud to make a 60 day coarse of treatment. From what I have read different cancers respond better to either THC or CBD, not sure which category your situation falls into.

Here are 2 links for legal high CBD meds. They are sold for pets so you will need to decide if that is an issue for you but thought it might at least be an option while you come up with something else or grow your own. Thanks Sniper and Root66 for the links


http://www.cannaforpets.com/

We are starting a RSO section on AFN, I will get you the info to request access, can't find it at the moment

Also check out Cancer and pH theory
https://www.autoflower.org/f64/cancer-treatments-ph-theory-26064.html

And here is another good medical cannabis site
http://www.medicaljane.com/

Good luck to you both
 
Wow gang. Thanks for the quick responses. I haven't had a chance to sort through it all yet and put it into context, but it seems like that is alot of what I do these days. Keep it coming and I will try to share info as well as I put sense to it all.
 
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