I didn't do a research on this topic via autoflower. Just came across this interesting discussion by a knowledgeable forum admin. May get some discussion going here.
https://www.greenpassion.org/index.php?/topic/1116-to-flush-or-not-to-flush/
https://www.greenpassion.org/index.php?/topic/1116-to-flush-or-not-to-flush/